StackWave Affinity™

This article is Part 5 in a 5 part series on the fundamentals of DrugOps.  In case you'd like to jump directly any of the other sections please find the links below:

• Part 1 - Intro to DrugOps
• Part 2 - Shared Ownership
• Part 3 - Transforming Sequence Analysis into an Automated Workflow
• Part 4 - Better Therapeutics through Rapid Feedback
  
• Part 5 - StackWave Affinity™, a fundamentally different approach to Antibody Discovery

A Fundamentally Different Approach to Antibody Discovery

At StackWave, we’ve been working with therapeutic discovery organizations for over a decade and have seen first-hand the challenges of managing antibody discovery teams, processes, and data. Disparate, fragmented, and often limited tools force scientists to spend their time typing, copying, importing, and exporting data instead of advancing their therapeutic goals. To tackle these challenges, we’ve drawn on our many years of experience working with scientists to create StackWave Affinity™. Affinity takes a fundamentally different approach than other software solutions to the unique challenges of Antibody Discovery teams.

Better Collaboration through Shared Ownership

Shared ownership is about breaking down silos and fostering a collaborative spirit across the organization. Affinity supports shared ownership of the data and processes that drive therapeutic development by:

• Providing insights into operational bottlenecks across the organization
• Tracing discovery results through all touch points back to their source
• Making it easy to aggregate, analyze, report on, and make decisions with system data

Antibody Discovery Workflow Automation

Our narrow focus on Antibody Discovery allows us to automate key discovery workflows and to capture all of the critical data necessary for advancing therapeutic candidates without the need for customization or costly implementations. A few examples of the workflows this narrow focus allows us to provide out-of-the-box are:

• Automatic clone and antibody sequence analysis to identify V(D)J germlines, CDRs, and potential sequence liabilities
• Screening, filtering, and handoff of lead clones from display, hybridoma, and single B-cell discovery platforms
• Protein expression request management from transfection through distribution into integrated inventory management

Rapid Feedback for Continuous Improvement

The ability to learn from previous campaigns is a crucial part of continuous improvement. Affinity provides the insights necessary to explore the history of each program across the organization and within each team to make evidence-backed improvements. With Affinity you can:

• Evaluate factors contributing to program progress against goals in real-time
• Explore the properties of leads out of each discovery platform to identify trends, risks, and biases
• Review turnaround times and production quality of expressed proteins to support process improvements

Sign up for a demo and let us show you how StackWave Affinity™ can support every part of your Antibody Discovery process, or sign up for a trial and discover its effectiveness for yourself.