Biologics R&D Platform

StackWave Affinity™

StackWave’s Affinity is the most comprehensive software platform for biologics R&D. Unlike other systems that graft an incomplete set of tools onto an ELN or chemical registry, Affinity was designed from the start for biologics R&D companies. 

Made for biologics R&D teams

The Most Comprehensive Software Platform for Biologics R&D

StackWave Affinity™ provides out-of-the-box support for in-vitro and in-vivo discovery; high-throughput screening and sequencing; vector design and verification; cloning, reformatting, and expression; inventory management; and characterization and reporting. Every plasmid, protein, cell, and sequence generates a complete read-out of properties, assay data, inventory, and associated information, and collects scientists’ comments to foster an ongoing asynchronous discussion.

With Affinity, there’s no need to purchase separate licenses for separate programs. Sequence analysis, project and campaign management, integrated inventory and ELN, custom plotting and reporting, built-in animal studies, and assay data ingest are all a part of the Affinity solution. Take advantage of our asset management product LabInspector to manage instruments, schedule usage, and track laboratory issues.

Click here to download the StackWave Affinity LIMS presentation

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Image of plasmid circular map with restriction sites
Image of antibody sequence regions
Image of clone lead identification plot
Image of sequence alignment for antibody region
Image of operational antibody project data
Affinity in Action

Manage your entire process

Support every step for every team with Affinity. Our platform covers your entire discovery and development process, from the launch of a new program to the initiation of a preclinical study and everything in between. Request a demo or free trial today.

Collaborate

Facilitate collaboration between discovery, production, and analytics teams

Integrate

Fully integrated, from target identification to lead characterization

Consolidate

Single source of truth for all assay data

Analyze

In-depth analysis of lead antibodies

LEARN MORE ABOUT AFFINITY MODULES

Comprehensive support for your entire discovery process

Planning

The structure of your R&D work: programs, their projects, and the biological targets each pursues, connected to the samples, assays, and leads they produce. Lay out phases on a live Gantt and bind a project dashboard that tracks where candidates stand against the program's goals as new data lands. 

 

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Bioregistry

One registry for every reagent: antibodies, plasmids, ADCs, multispecifics, cell lines, chemicals, and more. Sequence-aware from the start, with variable domains and CDRs called automatically. Each record connects to the clones, constructs, assays, and inventory around it, so a candidate's full picture is in one place. 

 

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Discovery

First-class support for phage and cell display campaigns, hybridoma and B-cell sorting and screening, and multispecific panel generation and evaluation. As clones are sequenced, variable domains and CDRs are called automatically, and the panel that comes out is ready for cloning, expression, and characterization.

 

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Molecular Biology

Design expression vectors in the browser from your own catalog of parts, or import an existing plasmid and edit the map directly, with reverse translation and simulated cloning built in. Carry each build through a tracked pipeline to a verified plasmid that lands in inventory with its lineage back to the originating clone and the project it serves. 

 

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Protein Production

From expression request to released lot, with the production data captured at every step. Standard and high-throughput expression run on one platform; every lot is reviewed against yield, concentration, purity, and endotoxin before release; and released lots land in inventory with their full production record attached.

 

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Inventory

A live picture of every freezer, shelf, box, and tube, connected to every aliquot and tied to the experiments those samples belong to. Scientists pull samples without hunting; lab managers see what's on hand without a spreadsheet; and the clones, proteins, and assays that come out keep their full history.  

 

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In Vivo

The whole animal study in one place: cohort enrolled into treatment groups, dosed against the live inventory, with measurements, mortality, and tissue collection captured on schedule. When the data is in, survival curves, per-group time-series, and dose-response fits run against the cohort the technicians recorded. 

 

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ELN

A structured lab notebook whose entries capture real records, each linked back to its source: the antibody from the registry, the sample from inventory, the assay result as measured. Entries are numbered, tagged, and searchable across every notebook; signed and witnessed with a full audit trail; with templates that make repeated procedures reusable. 

 

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Analysis

Turn raw instrument output and sequence data into structured, comparable results without leaving the platform. Capture from every instrument, fit dose-response curves, annotate antibody sequences and screen them for liabilities, identify clones from Sanger and NGS runs, and search and align across the whole registry that the rest of Affinity uses. 

 

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Reporting

Dashboards, candidate comparisons and profiles, and report pages that read directly from the same registry the rest of Affinity writes to. The ranked candidate list, the program dashboard, and the leadership report all reflect the data as it stands, not last week's export.

 

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SOFTWARE THAT WORKS FOR YOU

Hear what others are saying about StackWave

"StackWave gives us confidence in our leads by collecting all of the data about our potential therapeutics in one place and making that data actionable by allowing us to compare antibodies of interest."

"I worked with StackWave for ~4 years at my previous job to implement our LIMS. It was a great learning experience. We put in place an incredible system for our entire workflow, from plasmid registration to in-vivo study data registration."

"StackWave’s Platform allowed us to collaborate on our in-vivo studies in a web browser at home... I would highly recommend StackWave for therapeutic discovery teams looking to improve collaboration between teams."

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One Platform for Antibody R&D