Generate and evaluate leads from phage panning
The phage display technique of therapeutic antibody selection provides a means of capturing an enormous variety of natural and synthetic antibody repertoires for antibody discovery in phage libraries. However, keeping track of the different protocols and steps involved in a phage discovery campaign can be a challenge, especially when spread across different systems for note-taking, record-keeping, and assay data management.
Affinity provides a fully-integrated phage panning and selection process, from library creation, protocol design, and visualization through lead identification and hand-off. Supplement step-by-step instructions in your ELN with a graphical representation of your entire phage panning protocol, then easily generate sets of screening plates for assaying, sequencing, filtering, and analysis. Every set of filtered plates includes the filter that produced it and is linked back to its source plates to facilitate automation.
Instead of simply listing the steps in your phage protocols, graphically connect phage libraries, antigens, and other reagents to your rounds of selection, then generate multiple pools of phage output to seed subsequent rounds or to generate plates for screening. Combine assay data for screening plates in our clone filtering tools to whittle down to the desired set of leads, then use the built-in sequence analysis tools to identify unique antibodies for hand-off to molecular biology and protein expression teams. The system can be configured to generate scripts for different liquid handling platforms to automate the generation of filtered plates from source plates. Move your phage panning operations out of Excel and into the Affinity LIMS and eliminate the need for external sequence analysis and liquid handler automation tools.
Click here to download the StackWave Affinity LIMS presentation
