Register and manage variable region pairs by clone, sequence, or variable region
Variable Region Pair Registration
To register new variable region pairs, click on Register in the upper left of the Variable Region Pair index page and select by Clone, Sequences, or Variable Regions. This will open the appropriate registration form, which allows for manual data entry or XLS import for registration of larger numbers of Variable Region Pairs (VRP’s) at a time.
Variable Region Pair Index and Details
The index page allows users to review the existing VRP’s in the system. Filters can be applied on any column to narrow the displayed VRP’s. The Antibodies column will display a list of antibodies in the system with the same variable regions as the given pair. Click on an ID or name to navigate to its details page.
The details section will allow users with proper permissions to edit the Name, Description, and Targets of a VRP. It also includes calculated values, including Molecular Weight, Extinction Coefficient, and Isoelectric Point.
In the upper right of the page, the user is able to tag, comment, and attach any files to the entity.
The VH and VL of the pair are displayed, and each will have its own attributes, displaying the chain’s ID, molecular weight, extinction coefficient, isoelectric point, germline analysis, VGene, DGene, JGene, any clones which use this chain, any plasmids which can be used to construct this chain, and VR Analysis. Finally, there is a sequence map which displays the chain’s sequence along with the annotations associated with the selected pipeline. Select different pipelines to view different or more than one set of annotations at a time (i.e. both Kabat and Chothia).
