Brentuximab Vedotin works by targeting and binding to a protein known as CD30 on cancer cells.
Trastuzumab emtansine (T-DM1) is a combination of the chemotherapy drug called emtansine and the monoclonal antibody trastuzumab.
CD30 is expressed in some tumor cells, making it a potential target for cancer immunotherapy.
In normal cells, HER2 helps to regulate cell growth and division. However, in HER2-positive breast cancer, the cells produce too much of this protein.
Antibody-drug conjugates (ADCs) are therapeutic agents that consist of monoclonal antibodies that are linked to a small-molecule drug or a cytotoxic...
TNF inhibitors work by blocking the action of tumor necrosis factor, thereby reducing inflammation and relieving symptoms.
Interleukin-6, otherwise known as IL-6, is a cytokine that plays a key role in the inflammatory response of the body.
Identification of the appropriate target is a major part of drug discovery and development, as it is the starting point for drug design and...
Therapeutic drug discovery is an interdisciplinary approach to the development of new medicines.